Maklumat lanjut ― Melayu

Pigmented purpuric dermatoses (PPD) ialah sekumpulan keadaan kulit yang ditandai dengan kawasan kecil pendarahan di bawah kulit akibat keradangan kapilari. PPD biasanya bermula dengan bintik merah hingga ungu yang kemudiannya bertukar menjadi coklat keemasan apabila hemosiderin diserap semula.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.

Schamberg disease ialah jenis pigmented purpuric dermatoses (PPDs) yang paling biasa, iaitu keadaan kulit kronik yang dicirikan oleh bintik merah atau ungu kecil, dan peningkatan warna kulit (tompok coklat, merah atau kuning) . PPD dikelaskan kepada lima jenis: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura, and eczematoid-like purpura of Doucas and Kapetanakis. Schamberg disease (SD) juga dikenali sebagai progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressiva, and Schamberg's purpura. Ia terutamanya memberi kesan kepada lelaki dan biasanya muncul pada bahagian bawah kaki, tetapi juga boleh berlaku pada paha, punggung, batang atau lengan.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.

Maklumat mengenai 113 pesakit dengan PPD telah dianalisis, termasuk 38 yang menjalani biopsi kulit untuk kajian ini. Jenis klinikal yang paling biasa ialah penyakit Schamberg (60. 5%) . Keadaan lain di samping PPD ialah hipertensi (15. 8%) , diabetes (10. 5%) , dan lain-lain. Sejarah ubat mendedahkan statin (13. 2%) , penyekat beta (10. 5%) , dan lain-lain. Faktor-faktor yang mungkin dikaitkan dengan PPD termasuk jangkitan pernafasan atas baru-baru ini (5. 3%) , berdiri berpanjangan yang membawa kepada tekanan ortostatik tinggi (2. 6%) , dan senaman berat (2. 6%) . Rawatan telah diberikan kepada 36 pesakit (94. 7%) - oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.